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After extracting extraction and separating tobacco with grey speckled leaves, the main chemical component, 9.7 mg of YC-ZJF was isolated from the tobacco with grey speckled leaves by repeated high-performance liquid chromatography (HPLC)

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This composition is typical of UK e-cigarette user populations [29,30,31] and indicates that the overall finding for exclusive e-cigarette users is attributable to former smokers who switched to vaping rather than to never-smokers who took up e-cigarette use independently